Get ready for another jaw-dropping transformation from Renée Zellweger.
The two-time Oscar winner totally transforms into convicted murderer Pam Hupp in the first teaser for NBC's highly anticipated new show The Thing About Pam. Zellweger is nearly unrecognizable wearing body padding and facial prosthetics to embody the diabolical, soda-slurping killer.
The Thing About Pam is based on the 2011 murder of Betsy Faria that resulted in her husband Russ' conviction. While Russ was later exonerated the crime set off a chain of events that eventually exposed a villainous scheme planned by Pam.
The new teaser shows Pam being questioned by authorities asking, "Was he ever violent with Betsy?"
"I don't know, he seemed real aggressive," Zellweger replies innocently. "You know the type."
"I didn't do this!" Russ (played by Glenn Fleshler) insists in the clip.
However, investigators later learn that four days before Betsy's murder, "Betsy changed the beneficiary from Russ to Pam."
After Pam is shown laughing diabolically, he friend says, "Now you can afford that facelift you've been wanting."
"I don't know what you're even talking about," Pam replies.
Based on one of Dateline's most popular stories ever, the six-part series also stars Josh Duhamel, Judy Greer, Katy Mixon and more.
The Thing About Pam premieres Tuesday, Mar. 8 at 10 p.m. on NBC and streams the next day on Peacock.
Scroll through the photo gallery below to see more stars transform into real-life players for major roles.
(E!, NBC and Peacock are all part of the NBCUniversal family)
Timothée Chalamet as Bob Dylan
The Wonka star played the legendary folk singer-songwriter in the film A Complete Unknown.
Lily James as Pamela Anderson
The English actress transformed into the Baywatch icon in the Hulu series Pam & Tommy.
Sebastian Stan as Tommy Lee
The actor dropped jaws after showing off his epic makeover as the Mötley Crüe rocker for the Hulu series Pam & Tommy.
Christian Serratos as Selena Quintanilla
The actress portrayed the late Tejano star for the Netflix show Selena: The Series.
Charlize Theron as Megyn Kelly
The Oscar winner had fans doing a double-take in Bombshell, in which she played Fox News alum who helped take down Roger Ailes' career after he was accused of sexual misconduct.
Andra Day as Billie Holiday
The actress earned her first Golden Globe win in 2021 for her role as the iconic singer in the biopic The United States Vs. Billie Holiday.
Margot Robbie as Tonya Harding
The Australia native produced and starred in I, Tonya, a 2017 movie based on the disgraced figure skater's life.
Taron Egerton as Elton John
In 2019's Rocketman, the British actor played one of the most iconic musicians in the history of rock 'n' roll.
Jessica Lange as Joan Crawford
The Oscar winner stepped into the shoes of the late movie legend in Feud, Ryan Murphy's FX series about the making of What Ever Happened to Baby Jane?
Susan Sarandon as Bette Davis
The Dead Man Walking star played the acting legend in Feud.
Jennifer Hudson as Aretha Franklin
The singer took on the Queen of Soul in 2021's Respect.
Felicity Jones as Ruth Bader Ginsburg
After Natalie Portman dropped out, the English actress stepped in to play the late Supreme Court Justice in On the Basis of Sex, a biopic directed by Mimi Leder.
Anthony Mackie as Martin Luther King Jr.
The actor played the civil rights leader opposite Bryan Cranston as President Lyndon B. Johnson in HBO's All the Way.
Benedict Cumberbatch as Thomas Edison
The Oscar-nominated actor portrayed the famed inventor of the light bulb in Current War.
Tom Hiddleston as Hank Williams
The British actor starred as the late country singer in the 2015 film I Saw the Light.
Johnny Flynn as David Bowie
The Lovesick star played the late rock legend in the 2020 biopic Stardust.
Parker Sawyers as Barack Obama
Parker Sawyers played the former president in Southside With You, a romantic dramedy loosely based on Barack's first date with Michelle Obama back in 1989.
Tika Sumpter as Michelle Obama
The actress starred as the former First Lady in Southside With You.
Odette Annable as Trudy Cooper
"She was a groundbreaking woman, so ahead of her time," Odette told E! News of her Astronaut Wives Club character, who was an extremely skilled pilot in her own right. "It's such an honor to play her."
Kerry Washington as Anita Hill
The Scandal star took on the role of the aide who accused U.S. Supreme Court nominee Clarence Thomas of sexual assault in 1991 in HBO's biopic Confirmation.
Michael Keaton as Ray Kroc
The Oscar nominee starred in The Founder, a biopic about the founder of the McDonald's empire.
YaYa DaCosta as Whitney Houston
The actress and model played the late legendary singer in a Lifetime biopic.
Eddie Redmayne as Stephen Hawking
The Les Misérables heartthrob won the Oscar after portraying Hawking in Theory of Everything.
Katie Holmes as Jacqueline Kennedy
In The Kennedys miniseries, the Dawson's Creek alum channeled the former First Lady and one of America's most fashionable public figures.
Nicole Kidman as Grace Kelly
The Oscar-winning actress stepped into the regal shoes of the Hollywood legend turned princess for Grace of Monaco.
Scarlett Johansson as Janet Leigh
The Marvel star played Jamie Lee Curtis' famous mom in Hitchcock, which focused on the making of Alfred Hitchcock's Psycho.
Agnes Bruckner as Anna Nicole Smith
The former Private Pactice starlet portrayed the late Playboy model in the Lifetime biopic The Anna Nicole Story.
Ashton Kutcher as Steve Jobs
The That '70s Show alum played the late Apple co-founder in the indie flick Jobs.
Chris Hemsworth as James Hunt
The Aussie actor portrayed the Formula 1 race car driver in Ron Howard's biopic Rush.
Naomi Watts as Valerie Plame Wilson
The actress starred alongside Sean Penn as the outed CIA agent in the thriller Fair Game.