Christina Applegate

Four years after Christina Applegate shared her multiple sclerosis diagnosis, the Dead to Me actress detailed how her 14-year-old daughter Sadie is coping with her ongoing health journey. 

August 28, 2025

Christina Applegate shared how living with multiple sclerosis has “broken” her 14-year-old daughter Sadie.

August 28, 2025

Christina Applegate revealed she was hospitalized for a double kidney infection as she navigates living with multiple sclerosis.

August 6, 2025

Christina Applegate recorded the Aug. 5 episode of her podcast MesSy from her hospital room where she is currently being treated for a double kidney infection that left her in excruciating pain.

August 5, 2025

Christina Applegate mourned the death of her father, Robert ‘Bobby’ Applegate, in an emotional episode of her ‘MeSsy’ podcast.

April 29, 2025

Christina Applegate broke down in tears, sharing insight into her grieving process following the recent death of her father Robert Applegate.

April 29, 2025

Christina Applegate candidly shared the effects of her multiple sclerosis that has led to multiple hospitalizations since her diagnosis in 2021.

March 19, 2025

Christina Applegate, who was diagnosed with multiple sclerosis (MS) in 2021, shared new insight into her experience with the disease, saying, “I can’t even pick up my phone sometimes.”

November 6, 2024

Dead to Me’s Christina Applegate shared the warning she gives her friends before going out and said, which she prefaces with, “You can’t be mad.”

August 22, 2024

Christina Applegate—who was diagnosed with multiple sclerosis in 2021—opened up about what tool she finds “very useful” in her fight against the condition.

August 9, 2024

During the July 30th episode of her podcast, Christina Applegate shares the "only plastic surgery" procedure she's gotten done and why she felt pressured to do it.

July 31, 2024

Christina Applegate shared she had a plastic surgery procedure done at 27-years-old to remove the bags from under her eyes after a producer told her they were too big.

July 31, 2024

Christina Applegate detailed two big goals she hopes to achieve amid her battle with multiple sclerosis that began in 2021. 

July 3, 2024

Christina Applegate's daughter Sadie detailed how her recent diagnosis with POTS has helped her relate to her mother’s struggles with multiple sclerosis.

June 26, 2024

Selma Blair, who was diagnosed with multiple sclerosis in 2018 and announced in 2021 that she's in remission, shared with E! News how she's been feeling.

June 6, 2024

While discussing living with multiple sclerosis with Christina Applegate, on the MeSsy podcast, Jamie-Lynn Sigler shares the near-death experience she faced last year.

June 6, 2024

Christina Applegate opened up on her inability to “enjoy living” amid her multiple sclerosis diagnosis, which she first shared in 2021.

June 4, 2024

Christina Applegate—who contracted sapovirus amid her battle with multiple sclerosis—shared a look into the reality of wearing adult diapers.

April 25, 2024

The actress is detailing her recent battle with sapovirus, a virus commonly transmitted through fecal-oral contact, on the April 23 episode of her podcast.

April 24, 2024

Christina Applegate contracted sapovirus—a virus transmitted through fecal-oral contact—amid her battle with multiple sclerosis: "Someone else's poop went into my mouth and I ate it."

April 24, 2024

In honor of the Don't Tell Mom the Babysitter's Dead remake with Nicole Richie, we've compiled an exquisite QED report full of secrets about the 1991 cult classic starring Christina Applegate.

April 12, 2024

Christina Applegate vowed be frank about her struggles with multiple sclerosis—an autoimmune disease that affects the nervous system—no matter how painful it could get. Here's everything she's said.

March 30, 2024