Kristen Wiig
The hilarious actress has had roles in hit comedy movie after hit comedy movie, no one will ever forget her scene in Bridesmaids. Yes, we're talking about the whole "help me, I'm poor" moment that has now been turned into one of the Internet's favorite memes. Thank you, dear Kristen for that!
Tina Fey
While the comedian's many moments on Saturday Night Live as well as 30 Rock will forever go down in history as some of her best ever, in talking about films, we have to say her role in Sisters had us in tears from laughing so hard. We also must mention that she did write Mean Girls, and though her role in it wasn't her best, the movie itself is definitely a favorite!
Amy Poehler
Speaking of Mean Girls, it wouldn't be a funny gals list without Amy Poehler and her famous "I'm a cool mom" moment in the chick flick...duh!
Amy Schumer
The comedienne has made waves with her TV show Inside Amy Schumer as well as her hit film Trainwreck, which she not only starred in but also wrote.
Melissa McCarthy
Another comedienne who has had many, many hilarious roles both in movies and on television. However, if there's one moment in film that you connect with Melissa, we're guessing it would be the pooping scene in Bridesmaids. The second she dropped her drawers and headed to the sink, we knew we'd never get that image out of our minds!
Whoopi Goldberg
An oldie but a goodie, Sister Act is still one of our favorite flicks from the '90s and Whoopi Goldberg is the reason for that!
Isla Fisher
The red-headed actress' role in Wedding Crashers is, by far, her funniest. Case in point: the infamous scene during which she gave Vince Vaughn a hand-job underneath the dinner table. Hilarious!
Maya Rudolph
Obviously her time on Saturday Night Live is what brought her massive fame, but what about that one scene from Bridesmaids? Yes, you know the one we're talking about...In a wedding dress she hadn't yet purchased, forced to go No. 2 in the middle of the street. It still brings up belly aches from laughing so hard. Who thinks of this stuff!
Anna Kendrick
Other than winning a Tony Award at a very young age, nothing put Anna Kendrick on the map like her role in Pitch Perfect. Let's just say she was aca-hilarious!
Leslie Mann
The red head has been in some of the greatest comedies ever—including Big Dadd, 40-Year-Old Virigin and This Is 40. However, some of her most hilarious moments can be pulled from The Other Woman. The scene where she throws up in her bag, tries to kiss Cameron Diaz and then refuses to get in the taxi still has us in tears!
Kathryn Hahn
You might have just died laughing while watching her in Bad Moms, but this funny lady had us in tears with her role in Step Brothers. Remember her sex scene with John C. Reilly during Christmas dinner? Hilarious!
Rebel Wilson
When we think of funny ladies, this hilarious Australian definitely tops our list, thanks to her genius role as Fat Amy in Pitch Perfect!
Sandra Bullock
While we absolutely adored her in films like The Proposal and The Heat, her role in Miss Congeniality totally takes the cake. No one will ever forget that hilarious talent portion in which she taught us what it really means to S.I.N.G.
Anna Faris
From the Scary Movies to House Bunny, Chris Pratt's wife has brought us many laughs. However, we can't say we've ever giggled more than watching her play the crazy girlfriend next to Ryan Reynolds in Just Friends.
Elizabeth Banks
This funny gal has risen to the fame mostly due to her role as Effie in The Hunger Games, but her commentary throughout Pitch Perfect while playing Judge Gail always has us in a fit of laughter.
Emma Stone
We debated whether or not this funny gal's best moment came during Crazy, Stupid Love (you know, the shirtless Ryan Gosling scene) or Easy A. We finally landed on the latter because, let's be honest, her "Pocket Full of Sunshine" scene still gives us the giggles!
Christina Applegate
We can't even count on two hands the number of great performance Christina Applegate has put out there, but her role as Veronica Corningstone in Anchorman will definitely go down as an all-time favorite.
Reese Witherspoon
She's shown her range of films in everything from Walk the Line to Wild to Water for Elephants, but none of her roles had us laughing as hard as as her Gemini-vegetarian, pink-loving Elle Woods in Legally Blonde! We still use the bend-and-snap to this day!
Rose Byrne
We loved her in Neighbors and Spy, but nothing beats her hilarious role as the unhappy, people-pleaser and slight b--ch in Bridesmaids. Her poem dedicated to Maya Rudolph still makes us giggle!
Cameron Diaz
The blonde bombshell first got us giggling with her role in There's Something About Mary, but we have to say one of her most hilarious films is Bad Teacher. From the sex scene with Justin Timberlake to her car washing moment, she had us cracking up the whole movie!
Drew Barrymore
The 41-year-old actress has had us giggling since her first big role in E.T. in 1982. But we have to say one of her best comedic roles was in 50 First Dates. She was not only funny but totally charming, too!
Jennifer Lawrence
While she may not play a ton of goofy roles in films, J.Law is still one of our favorite funny ladies. From the comments she says on the red carpet to the faces she makes for the cameras, she always has us busting up with laughter!