Nikki Glaser
The Welcome Home Nikki Glazer star moved back to her hometown of St. Louis and in with her parents at the beginning of the COVID-19 pandemic.
Jon Hamm
Mad Men's Jon Hamm was born and raised in "The Gateway City."
Andy Cohen
Before becoming Bravo's No. 1 host, Andy Cohen spent his early years in the famous Missouri city.
Karlie Kloss
Model and TV host Karlie Kloss hit the streets of "The River City" long before she hit the runway.
Sterling K. Brown
Unlike his This Is Us character's hometown of Pittsburgh, Sterling K. Brown grew up a few states over in St. Louis.
SZA
This Grammy Award-winning singer is one of many famous musicians from the "Gateway to the West."
Jenna Fischer
Though she was born in Fort Wayne, Indiana, The Office star Jenna Fischer primarily grew up in St. Louis.
Ellie Kemper
Born in Kansas City, Missouri, Unbreakable Kimmy Schmidt star Ellie Kemper moved to St. Louis with her family at a very young age.
Evan Peters
This Emmy-winning actor was born and raised in St. Louis before rising to fame on American Horror Story.
Taylor Momsen
Long before she was Jenny Humphrey on Gossip Girl, this singer, model and actress was born in the "Rome of the West."
Nelly
Originally from Austin, Texas, rapper and singer Nelly moved to the suburbs of St. Louis with his mother as a teen.
Cedric the Entertainer
Born in the state's capital Jefferson City, Cedric the Entertainer moved to "The Mound City" with his family in his youth.
James Gunn
Before making it big in Hollywood, the Guardians of the Galaxy and Suicide Squad director grew up in St. Louis with his brother, actor Sean Gunn.
Akon
Though he considers himself more of a native of Senegal, Akon was born in the Midwest city.
Phyllis Smith
Another The Office alum, Phyllis Smith is also a St. Louis native.
Kevin Nealon
Comedian and former Saturday Night Live cast member Kevin Nealon was born in St. Louis before moving to Connecticut at just a few months old.