Kate Winslet & Leonardo DiCaprio
The pair first met while playing lovers in Titanic over 20 years ago and have remained friendly ever since. In 2017, Kate told People, "He's a solid, loyal person. He's a great friend, he always has been, and not just to me, but to everyone around him."
Vanessa Hudgens & Ashley Tisdale
Gabriella and Sharpay may not have been best friends, but Vanessa and Ashley are! The duo met while filming High School Musical in 2005 and have continued to hang out since. They even did the duet we always hoped for by singing "Ex's and Oh's."
Camila Mendes & Lili Reinhart
Our favorite Riverdale BFFs are BFFs in real life too! The pair is often seen being goofy together with Camila even telling Seventeen Magazine, "It's almost like we speak our own language."
Tina Fey & Amy Poehler
We would love to third wheel this funny friendship! The friends met in 1993 and since then have been frequent co-stars, award show co-hosts and best friends.
Kim Kardashian & Chrissy Teigen
John and Chrissy + Kanye and Kim = double date goals. The two couples have been spotted hanging out together with the girls forming an especially close bond. Kim attended a baby shower for Chrissy and surprised her with a huge bouquet after the birth of her second child.
Eva Longoria & Victoria Beckham
A fashionable duo! Victoria and Eva have been besties for years and give each other style inspiration. Victoria even designed Eva's dream wedding dress and named a shoe in her collection called "The Eva Pump" after her friend.
Serena Williams & Meghan Markle
The tennis star became friends with the Duchess of Sussex long before she became a royal. Serena was invited to Meghan's nupitals to Prince Harry and says that even though her friend now has a title, their "friendship is still exactly the same. We always have supported each other."
Nina Dobrev & Julianne Hough
These best friends met through their hairstylist and have been tight ever since. The pair has been there for each other through birthdays, vacations and life milestones. In fact, Nina was a bridesmaid in Julianne's 2017 wedding!
Jennifer Lawrence & Amy Schumer
These hilarious friends bonded over their shared sense of humor and became extremely close. Jennifer was one of the few guests at Amy's intimate wedding, and even gave a toast to the new couple!
Kim Kardashian & Serena Williams
The Keeping Up With the Kardashians star told Vogue that the two have been friends for more than 15 years. She also said to the publication, "Serena's the girl you can call and say anything to. She'll never judge you, and she's never too busy for you. Oh, and she can keep any secret."
Brad Pitt & George Clooney
After meeting on the set of Ocean's Eleven, the pair bonded over their shared goofy side. During the filming of Ocean's Twelve, the two had a prank war with Brad sending a memo to the crew that no one should make eye contact with George. His friend responded by putting a sticker on Brad's car that said, "Small Penis on Board."
Selena Gomez & Taylor Swift
These triple threats met backstage at a Jonas Brothers concert in 2008 and have been there for each other through happiness and heartbreak. Selena recently joined her friend on stage at her reputation tour, with Taylor writing on Instagram, "To the person I could call at any time of day, who has been there no matter what... you absolutely KILLED IT tonight and everyone was so excited to see you."
Michelle Williams & Busy Philipps
The pair met on the set of Dawson's Creek and have been there for each other through life's ups and downs. The friends are often each other's dates for award shows with Michelle even telling People, "I'm so in love with her. She's proof that the love of your life does not have to be a man! That's the love of my life right there."
Jennifer Aniston & Courteney Cox
These Friends co-stars are every bit as close as their iconic characters. They have been supportive of one another for years with Jennifer telling More, "There's absolutely no judgment in Court. You'll never feel scolded. She's extremely fair, ridiculously loyal and fiercely loving."
George Clooney & Rande Gerber
Rande is part of George's closest group of friends, which he calls "The Boys." He even told MSNBC that George gave each of the 14 members of the friend group a gift of one million dollars to thank them for their support over the course of his career.
Oprah Winfrey & Gayle King
These ladies first met in 1976 when working for a Baltimore television station and have been best friends ever since. They have both built their own empires, but supported each other the whole way. Oprah told O Magazine that they have a friendship where she, "wants the best for you in every single situation of your life. Lifts you up. Supports you. Always! That's an incredibly rare thing between even the closest of friends.
Penelope Cruz & Salma Hayek
These look-a-likes are best friends! They're so close, they once started romance rumors after Penelope was photographed grabbing Salma's butt. Penelope said on the Late Show with David Letterman, "We are like sisters and we have some sense of humor. We did that in front of 100 photographers. And the story now is that we are lovers."
Matt Damon & Ben Affleck
The pair met when they were only eight years old, and have remained tight into adulthood. They catapulted into stardom together after co-writing Good Will Hunting, and have since supported each other in their successful careers.