Michael Bolton Details Battle With Rare, Aggressive Form of Brain Cancer

Michael Bolton opened up for the first time about his battle with glioblastoma, a rare and aggressive form of brain cancer, over a year after sharing his brain tumor diagnosis.

By Hayley Santaflorentina Apr 30, 2025 1:25 PM
| Updated Apr 30, 2025 2:58 PM
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Watch: Michael Bolton Details Battle With Rare, Aggressive Form of Brain Cancer

Michael Bolton is determined to go the distance.

More than a year after the 72-year-old shared his brain tumor diagnosis—which he’s since confirmed to be glioblastoma, an aggressive form of brain cancer­—Michael is opening up about his journey with the disease.

“You’re reaching into your resources and your resolve in a way that you never would have thought,” he told People in an interview published April 30. “Succumbing to the challenge is not an option. You’re really quickly drawn into a duel. I guess that’s the way you find out what you’re made of.”

After undergoing emergency surgery in December 2023—which removed the entirety of the tumor—Michael has since undergone a second brain surgery due to an infection, comma as well as radiation and chemotherapy treatment, which he finished in October. He undergoes MRIs every two months to monitor for tumor recurrence, and his most recent scan, according to the outlet, looked clear.

Throughout this, he’s asked doctors not share his prognosis with him, as he prefers to remain positive.

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“I find comfort in general more easily,” he said. “[The whole experience] gives me a heightened sense of appreciation. It’s unthinkable for it to be okay not to make the most of your life. I think we develop capabilities and problem management, and we learn how to make the best out of a bad situation.”

He continued, “You have to be a cheerleader for yourself.”

Medios y Media/Getty Images

The experience has also changed the way the singer—who is dad to daughters Isa, Holly and Taryn, through whom he has six grandchildren—thinks about the legacy he wishes to leave behind. One that goes beyond the concrete legacy he’s already created through his music.

“How do I give things that they can take forward?” he reflected about his daughters. “Life lessons, love, any kind of validation that I can give—I want to be on the right side of that so they feel great about who they are.”

He added, “It’s a reality of mortality. Suddenly a new light has gone on that raises questions, including, ‘Am I doing the best that I can do with my time?’”

Facebook/Michael Bolton

And for the six-time Grammy winning artist, he’s determined to make sure the time he has left is as long as possible.

“I want to keep going. I feel there’s still a lot to do on the fight side,” he explained. “I got a title for a song: ‘Ain’t Going Down Without a Fight.’”

And his family will be there every step of the way. As Taryn noted, “We’re in this together, and that’s it.”

For more celebrities who have shared their experiences with cancer, keep reading.

Colin Egglesfield

The All My Children alum announced in January 2025 that he had been diagnosed with prostate cancer, his third cancer diagnosis throughout his life.

Despite the devastating news, he announced (for the third time) in February 2025 he was cancer-free following successful surgery and treatments.

“Remember, you’re not defined by any of your challenges," he wrote in his February 2025 Instagram update. "You’re grander than it all. I’m not my fear, my anxiousness or my scars but I embrace it all because the only way to transform it is to own it.”

Gerry Turner

The former Golden Bachelor star shared in Dec. 2024 that he had been diagnosed with Waldenström's macroglobulinemia, a bone cancer.

"Unfortunately, there's no cure for it,” Gerry noted to People at the time. “So that weighs heavily in every decision I make. It was like 10 tons of concrete were just dropped on me. And I was a bit in denial for a while, I didn't want to admit to it.”

Jim Beaver

The actor, known for roles in The Boys and Supernatural, shared on Feb. 3, 2023, that he had battled prostate cancer for years and was cancer free.

Ariana Madix

"I had to have a lil bit o'cancer removed from my body and lymph nodes biopsied," the Vanderpump Rules star revealed to fans at the close of 2018. "(In the clear now!)"

Marcia Cross

The Desperate Housewives star revealed to fans in September 2018 that she survived anal cancer. "After posting a picture of myself here and uttering the words #cancer and #hairloss, I feel liberated, deliriously free and completely me," she shared on Instagram

Dustin Hoffman

The two-time Oscar winner underwent successful treatment for cancer, and his rep confirmed to E! News that doctors deemed Hoffman "surgically cured."

Hugh Jackman

The X-Men star was treated for his third basal cell carcinoma back in 2014, and after his third treatment, Jackman's rep told E! News that he's "all good" now.

In April 2023, Hugh had two biopsies for additional basal cell carcinoma. At the time, he told fans, "If I can just take this opportunity to remind you summer is coming for those of us in the northern hemisphere, please wear sunscreen."

Camille Grammer

The former Real Housewives of Beverly Hills star celebrated one year of being cancer-free in January. The mother of two was diagnosed with endometrial cancer back in 2013 and underwent a radical hysterectomy.

Then in 2017, Camille had surgery to remove Squamous Cell Carcinoma, a type of skin cancer. 

Gordon Ramsay

Alongside a pair of photos that show a line of stitches running from the bottom of his ear to his jaw, which he later covered with a bandage, the British celebrity chef shared that he underwent a procedure to treat skin cancer.

“Grateful and so appreciative for the incredible team at The Skin Associates and their fast reactive work on removing this Basal Cell Carcinoma,” Gordon wrote on Instagram August 2025. “Please don’t forget your sunscreen this weekend.”

“I promise you it’s not a face lift,” he added. “I’d need a refund…”

Cobie Smulders

The Avengers: Age of Ultron actress battled ovarian cancer at the age of 25 and overcome odds when she welcomed two children with husband Taran Killam.

Dr. Drew Pinsky

TV host reveals he underwent surgery for prostate cancer in July 2013 and has since been given a clean bill of health.

Brooke Burke

The Dancing with the Stars cohost underwent successful surgery for thyroid cancer. The mother of four tweeted, "Thx for all the twitter love. I'm [home] recovering & resting."

Angie Everhart

"MY DR CALLED ME ON A SAT. MORNING TO TELL ME I AM CANCER FREE!!!!! #wootothemotherf--kinhoo," the actress tweeted after receiving the good news.

Christina Applegate

The Up All Night star was declared "100-percent clear" of breast cancer after treatment and a double mastectomy.

Michael C. Hall

The Dexter star used a hiatus from his hit series to slay Hodgkin's lymphoma.

Michelle Monaghan

The Australian actress revealed in October 2011 that she had a cancerous mole removed from her calf after her hubby encouraged her to get the suspicious-looking mark checked out.

Ewan McGregor

The Scot is trainspotting just fine these days after having a cancerous mole removed from beneath his right eye.

Sheryl Crow

The singer beat breast cancer in 2004 with a "minimally invasive" lumpectomy and radiation therapy.

Michael Douglas

The Oscar winner declared in early 2011 that his tumor was gone and he had throat cancer "beat."

Edie Falco

The Emmy winner whacked breast cancer in 2004.

Anderson Cooper

Surely the CNN veteran wears his SPF when he's braving the elements now after having a cancerous growth removed from under his left eye in 2008.

Kylie Minogue

The Australian pop star underwent successful surgery for breast cancer in 2005.

Barry Watson

The 7th Heaven star was diagnosed with Hodgkin's disease when he was only 28. He's 50 now and looking good!

Maura Tierney

The ER fave had to abandon her role in Parenthood to fight breast cancer in 2009—but her treatment was a success and she was back on the red carpet in no time.

Sharon Osbourne

The America's Got Talent judge was diagnosed with colon cancer while shooting The Osbournes in 2002 and used the opportunity to stress the importance of regular screenings while attacking the #@%! with chemotherapy. She was declared cancer-free the following year.

Robert De Niro

The Oscar winner took prostate cancer down, down to Chinatown, in 2003, and has been in about 400 movies since then.

Robin Roberts

The Good Morning America cohost proudly flaunted her smooth scalp while undergoing chemotherapy to treat breast cancer in 2007.

Lance Armstrong

The champion cyclist battled back from stage-four testicular cancer before winning seven straight Tour de France titles.

Melissa Etheridge

The Grammy and Oscar winner became an inspiring activist after a lumpectomy and chemotherapy cleared her of breast cancer in 2005.

Julia Sweeney

The former Saturday Night Live standout mined her breast cancer battle for comedic material that turned into God Said Ha!, her successful one-woman show that eventually went to Broadway.

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