Danny Trejo
The actor plays Machete Cortez, who battles his way through Mexico to take down a billionaire arms dealer.
Sofia Vergara
The Modern Family actress transformed from a sexy housewife to a sexy hitwoman for her role as Madame Desdemona.
Charlie Sheen
Machete is enlisted by the President, played by none other than Charlie Sheen.
Amber Heard
The blond beauty plays Miss San Antonio, who carries blades with her everywhere she goes.
Lady Gaga
And then there's La Chameleón, who is ready for some of the action.
Amber Heard & Danny Trejo
Miss San Antonio seduces Machete...will he be able to resist her?
Alexa Vega
Vega has described her character KillJoy as the "bodyguard of a whore house."
Danny Trejo & Michelle Rodriguez
You don't want to mess with them.
Charlie Sheen
Mr. President is not one to stand down in this arms race.
Lady Gaga
Lady Gaga channels her inner Marilyn Monroe, with a killer twist.
Sofia Vergara & Alexa Vega
How badass do they look?!