Jeremy Renner
The Hurt Locker star is in talks to star alongside Tom Cruise in Mission: Impossible IV, and, as rumor has it, possibly take over for the franchise should Cruise feel like retiring.
John Cusack
The Hot Tub Time Machine star is taking a serious turn and has confirmed he'll be starring in a big-screen version of Edgar Allen Poe's The Raven.
Angelina Jolie
Jolie's been tapped to star in a big-screen version of the British miniseries Unforgiven, about a woman released from prison for murdering two policemen. While she tries to live a peaceful life, the sons of one of her victims are out for revenge.
Rachel McAdams
The former Mean Girl stars alongside Channing Tatum in the story of newlyweds recovering from a car accident that has left one of them with severe memory loss.
Hilary Swank
The two-time Oscar winner stars in Conviction, the true story of a sister who dedicates her life to overturning her brother's murder conviction. Sam Rockwell, Minnie Driver and Melissa Leo also star.
Andie MacDowell
The actress is the newest addition to the cast of the Footloose remake. She's set to star as the wife of the town's rigidly strict reverend, who'll be played by Dennis Quaid.
Channing Tatum
The G.I. Joe star will be attending his high school reunion in the upcoming flick Ten Year, which focuses on a group of friends getting together a decade after graduation.
Sam Worthington
The Avatar star is gearing up to play a journalist/photographer in the surfing drama Drift. Based on a true story, the movie follows surfing's evolution as a beach pastime into a billion-dollar, worldwide industry.
Anna Paquin & Kristen Bell
The True Blood hottie and erstwhile Veronica Mars star have joined the cast of the upcoming Scream 4. Filming on the Wes Craven-directed flick is under way in Michigan. The actresses will be joining Scream vets Neve Campbell, Courteney Cox and David Arquette.
Katie Holmes
Mrs. Tom Cruise will star alongside Adam Sandler and Al Pacino in the comedy Jack and Jill. In the flick, Jack (Sandler) is a family man plagued by a Thanksgiving visit from his twin sister, Jill. Holmes is set to play Jack's wife.
Jessica Alba
Mommyhood never felt so cool. The Fantastic Four actress is getting into the secret agent game as she's come aboard Spy Kids 4: All the TIme in the World, director Robert Rodriguez's reboot of his popular tween franchise. She'll play a superagent and mother of a new pair of Spy Kids who's been recently reactivated.
Dolly Parton & Queen Latifah
The country celeb and hip-hop heroine are teaming up for a dynamite duet—this time, in a musical (natch) called Joyful Noise. Set to rescue a small-town choir from shutting down, Dolly and the Queen fight to (literally) save the music in this flick.
Sandra Bullock & Tom Hanks
The two Oscar winners are teaming up for Extremely Loud and Incredibly Close.
Jim Carrey
The funnyguy is set to star in Mr. Popper's Penguins, a film about a businessman who inherits—you guessed it—a flock of penguins.
January Jones
The Mad Men beauty has signed on to play the telepathic Emma Frost in X-Men: First Class. She joins stars James McAvoy, Michael Fassbender, Zoe Kravitz and Rose Byrne for the mutant flick, due in theaters in June 2011.
Max Von Sydow
The Exorcist star is the latest addition to the U.S. version of The Girl With the Dragon Tattoo. Check out our Five Things for all you need to know about Rooney Mara, who snagged the role of Lisbeth Salander.
Alexander Skarsgård
The True Blood hottie is set to star with Friday Night Lights' Taylor Kitsch and Sports Illustrated swimsuit babe Brooklyn Decker in the big-screen version of the game Battleship.
Rooney Mara
The search is over! After months of rumors and speculation (Will Kristen Stewart get the part? Natalie Portman maybe?), The Girl With the Dragon Tattoo has its lead.
Rose Byrne
The Damages star is the latest addition to the X-Men: First Class cast. She'll play Moira MacTaggert, an authority on genetic mutation, as well as the romantic interest of James McAvoy's Professor Charles Xavier.
Kristen Bell
The erstwhile Veronica Mars star is taking to the big screen for Dance of the Mirlitons. Bell is set to play the overbearing mother of an ambitious, slightly overweight young ballerina who will stop at nothing to become a star.
Michael Vartan
The former Alias star is set to share the screen with Zoe Saldana in the action flick Colombiana, about a woman hell-bent on getting revenge after her parents are murdered. Produced and cowritten by Luc Besson, it's sure to be a wild ride.
Isaiah Mustafa
More great news for the Old Spice Guy. Instead of appearing in two of three scenes in Tyler Perry's upcoming For Colored Girls Who Have Considered Suicide When the Rainbow Is Enuf, Mustafa is now set to take the lead in Perry's latest Madea installment, Madea's Big Happy Family.
Channing Tatum
The Dear John and G.I. Joe star is set to star in—and also produce—the big-screen adaptation of The Contortionist's Handbook. Tatum will play a forger who moves from one identity to the next to avoid getting caught.
Cillian Murphy
The Inception star is on a roll! Fresh off the heels of his turn opposite Leo DiCarprio in the Chris Nolan dream thriller, Murphy is now set to star alongside Justin Timberlake and Amanda Seyfried in I'm.mortal.