State of Affairs
In the NBC thriller, CIA analyst Charlie Tucker (Katherine Heigl) is chosen by the president (Alfre Woodard) to handle the most critical security issues that threaten the nation.
The Big Wedding
When Lyla Griffin (Heigl) and her family reunite for her adopted brother's wedding, a whole bunch of secrets and lies are exposed.
One For the Money
Recent divorcee Stephanie Plum (Heigl) lands a job as a bounty hunter at her cousin's bail-bond business and her first assignment is to track down a former cop who is also her former lover.
Life As We Know It
Holly Berenson (Heigl) and Eric Messer (Josh Duhamel) can't stand each other, but they are forced to put their differences aside after their mutual friends die in a car accident and they adopt their orphaned baby girl.
Killers
Jen Aimes (Katherine Heigl) believes she has found her dream man in her husband Spencer (Ashton Kutcher), who happens to be a retired assassin. Their blissful lifestyle takes a chaotic turn when they realize that their neighbors have been contracted to kill them.
The Ugly Truth
Abby Richter (Heigl) is a morning show producer who is unlucky in love until she hires a chauvinistic host (Gerard Butler) who helps her boost ratings and find the perfect man.
27 Dresses
The actress stars opposite James Marsden in this romantic comedy about Jane Nichols (Heigl), a woman who is always the bridesmaid—27 times, to be exact—but never the bride.
Knocked Up
In the Judd Apatow-directed comedy, Heigl's Allison Scott gets way more than she bargained for when she finds out she's pregnant after a one night stand with slacker Ben Stone (Seth Rogen).
Grey's Anatomy
The actress won an Emmy award for her portrayal of Dr. Izzie Stevens on Shonda Rhimes' popular medical drama about the professional and love lives of surgeons at Seattle Grace Hospital.
The Ringer
Steve Barker (Johnny Knoxville) poses as a contestant in the Special Olympics to solve his financial problems and falls in love with volunteer Lynn Sheridan (Heigl) during the competition.
Roswell
In her first television role, the actress portrayed alien-human hybrid Isabel Evans on the WB sci-fi series.