Kristen Wiig
The 45-year-old actress livened up the stage when she performed her Fay Fontaine sketch last year. Wearing a big, blonde Dolly Parton-esque wig, sunglasses as large as Iris Apfel's bifocals and a glam outfit, Wiig's skit was just as good as her Target lady character.
Derek Connolly and Bryan Cranston
The screenwriter was literally speechless during his acceptance speech for Best First Screenplay in 2013. He won for Safety Not Guaranteed, but he was so shocked over the win, he couldn't spit out the right words. Bryan Cranston came to the rescue and went on stage to pour Connolly a glass of liquor to loosen up. It most certainly helped.
Mickey Rourke
Giving one of the more odd acceptance speeches in the history of awards shows, Mickey Rourke talked about everything from Eric Roberts' career to beating "someone's ass" to admitting he couldn't remember who to thank.
Steve Coogan and Frank Coraci
Audience members thought Christan Bale and Joaquin Phoenix were taking the stage to present Best Documentary in 2009, but instead Steve Coogan and Frank Coraci walked out. Coogan rocked a Batman costume while Coraci wore a very Joaquin-inspired outfit.
Andy Samberg
The comedian and former SNL star made the In Memoriam portion of the broadcast a lot more nostalgic with his Breakfast Club-themed tribute. He not only recreated the famous fist-in-the-air scene, but he emulated Judd Nelson's character by wearing the iconic red plaid shirt and gray overcoat.
Rainn Wilson
The Office star admitted that most people probably thought he was too much of a "sitcom guy" and "not a hardcore indie badass" to host the star-studded show. So he enlisted Dennis Hopper to help him earn his "indie stripes." It was one of the more wacky skits to happen at an awards show.
Bill Murray
Another fun and quirky acceptance speech came courtesy of the 68-year-old actor. In true Bill Murray fashion, the comedian made a joke of how "independent" his speech was. "I have no prepared remarks," he began. "I didn't feel that would be independent."
Andy Samberg and Jack Black
When the 40-year-old actor couldn't get Quvenzhané Wallis to appear in his Beast It skit, he asked Jack Black to star in it.
Ally Sheedy
The actress made sure to soak up her acceptance speech moment after winning Best Female Lead for High Art. "I've never been nominated for anything before, this may never happen again," she started off, adding, I'm taking my f-----g time."