Wanda vs. Bella Swan
Wanderer aka "Wanda" is the parasidic alien "Soul" that latches on to Melanie's body (both played by Saoirse Ronan) in The Host and must deal with issues of morality and love.
Kinda like Bella (Kristen Stewart) in Breaking Dawn, a human in love with a vampire who gives her life to be with him.
Silver Surfer vs. Edward Cullen
In Fantastic Four: Rise of the Silver Surfer, the titular Silver Surfer is an alien from Zenn-La who gets powers from his flying surfboard and destroys planets. Oh yeah, and his silvery humanoid body glistens in sunlight.
Remind you of anyone? Maybe a certain vamp with the glittery body of a killer? That's right, Robert Pattinson in Twilight!
Thor vs. Eric Northman
Thor (Chris Hemsworth in Thor and then in The Avengers) is a Norse god from Asgard, son of Odin, who travels to Earth with his hammer of justice to protect humankind. And look hot while doing it.
Makes us think about another blond hottie: Bad boy bloodsucker Eric Northman (played by Alexander Skarsgård) on HBO's racy drama True Blood.
Superman vs. Stefan Salvatore
Two hunks with big hearts: First, there's Superman (most recently played by Henry Cavill in the upcoming Man of Steel), an alien named Kal-El from Krypton who is sent to Earth as a baby and grows up to become a superhero.
Then there's The Vampire Diaries' Stefan (played by Paul Wesley) a "blood addict" who abandons his vampire desires and falls for a human.
Seven of Nine vs. Queen Akasha
Born a human, Star Trek: Voyager's Seven of Nine (played by Jeri Ryan) was assimilated by an alien race called the Borg. Her most defining trait? Not her cybernetic implants, but that flashy silver catsuit!
Another flashy dresser: Akasha of The Queen of the Damned (played by the late Aaliyah), the first vampire and quite the fashionable (and deadly) force to be reckoned with.
Barbarella vs. Santanico
So Barbarella (played in all her vampy, space-stripping glory by Jane Fonda) may not technically be from outer space, but she spends enough time there bouncing between planets and hitting the sack with aliens that we say she counts.
Vampire queen Santanico Pandemonium (Salma Hayek in From Dusk till Dawn) has quite the saucy reputation too: She's the main attraction at the Titty Twister!
Megamind vs. Louis de Pointe du Lac
This one is more of a connection by association. First, there's Megamind (voiced by Will Ferrell in the animated movie of the same name), a super-intelligent alien supervillain who constantly battles Metro Man (voiced by Brad Pitt).
And Brad Pitt has played a suave vampire in Interview with the Vampire: The Vampire Chronicles!
Spock vs. Angel
Star Trek's Spock (played most recently by Zachary Quinto) is half human and half Vulcan (an alien race from the planet Vulcan); the latter is what influences his desire to live by reason and logic instead of emotion.
Angel (David Boreanaz of Buffy the Vampire Slayer and then Angel) runs on different emotions: Guilt and remorse, for the crimes he committed as a bloodsucker.
Neytiri vs. Selene
Neytiri te Tskaha Mo'at'ite (Zoe Saldana via some super impressive CGI) is a Na'vi princess on the planet of Pandora. She's a fierce warrior who also happens to have sex via interlacing tentacle tails (fun fact!).
Another exotic beauty: Underworld's Selene (Kate Beckinsale), a badass vampire who wages war against the Lycan werewolves.
Number Six vs. Rosalie Hale
Battlestar Galactica's Number Six (as portrayed by Tricia Helfer) is a type of Cylon who looks like a human. Sixes are known for being seductive, so it helps that they're drop-dead gorgeous (Helfer is a real-life model, FYI).
Though Twilight's Rosalie (Nikki Reed) is equally gorgeous, she isn't ususally one to seduce. She's standoffish at best, and an angry bitch at worst.
E.T. vs. Abby
This is a competition for the little guys: In one corner, E.T. (of E.T.), an adorable little extraterrestrial, who bonds with a human boy while trying to phone home.
Just as adorable, though far more deadly, is Abby in Let Me In (played by Chloë Grace Moretz), a young vamp who strikes up an unlikely friendship with a human boy.
Vampires, serial killers and aliens galore: Check out Hollywood's Top Monsters!