Accidentally on Purpose
What: Jenna Elfman stars in this delightful sitcom about an unwed movie critic mother whose much younger baby daddy moves in and brings his gang of ne'er-do-well friends with him.
When and Where: Monday, Sept. 21 at 8:30 p.m. on CBS
The Beautiful Life
What: America's Next Top Model, Make Me a Supermodel, Models of the Runway, meet The Beautiful Life, a scripted series about hot young things living in the high-stakes fashion industries of New York City. Mischa Barton costars as troubled model Sonja Stone.
When and Where: Wednesday, Sept. 16 at 9 p.m. on the CW
Brothers
What: NFL standout Michael Strahan joins Carl Weathers, CCH Pounder and sitcom veteran Daryl "Chill" Mitchell star in this family comedy about a former NFL player and his paraplegic, bar-owning brother.
When and Where: Friday, Sept. 25 at 8 p.m. on Fox
Community
What: Joel McHale, Chevy Chase and Gillian Jacobs star in Community, a hilarious comedy about a gang of lovable losers trying to improve themselves at a community college.
When and Where: Thursday, Sept. 17 at 9:30 p.m. on NBC
Cougar Town
What: Courteney Cox (and the fabulous Busy Philipps) return to television in a romantic comedy about suburban life and age-inappropriate relationships.
When and Where: Wednesday, Sept. 23 at 9:30 p.m. on ABC
Eastwick
What: Lindsay Price, Rebecca Romijn and Jaime Ray Newman star in Eastwick, a Desperate Housewives-y TV version of the cult-classic 1987 movie.
When and Where: Wednesday, Sept. 23 at 10 p.m. on ABC
Flash Forward
What: In this highly anticipated genre series starring John Cho and Joseph Fiennes, everyone on earth gets a two-minute sneak preview of their lives six months in the future.
When and Where: Thursday, Sept. 24 at 8 p.m. on ABC
The Forgotten
What: Christian Slater stars in this Jerry Bruckheimer procedural about amateur investigators who try to identify anonymous murder victims.
When and Where: Tuesday, Sept. 22 at 10 p.m. on ABC
The Good Wife
What: ER star Julianna Margulies stars as a political spouse beginning to work outside the home as a lawyer after being betrayed by her high-powered scumbag husband (Chris Noth).
When and Where: Tuesday, Sept. 22 at 10 p.m. on CBS
Hank
What: TV vet Kelsey Grammer gets in touch with the times as a former millionaire forced to cope with a downsized home and a disappointed family.
When and Where: Wednesday, Sept. 30 at 8 p.m. on ABC
Melrose Place
What: Squee! The CW's highly anticipated relaunch of Melrose Place brings juicy nighttime melodrama back to TV. Original series stars Laura Leighton and Thomas Calabro join a great-looking and talented cast of new kids. Don't miss the sexy fun!
When and Where: Tuesday, Sept. 8 at 9 p.m. on CW
Mercy
What: Want still more TV nurses after a summer of Nurse Jackie and Hawthorne? Then check out Mercy starring Georgina Sparks Michelle Trachtenberg, James Tupper and newcomer Taylor Schilling.
When and Where: Wednesday, Sept. 23 at 8 p.m. on NBC
The Middle
What: Comedy vets Neil Flynn and Patricia Heaton put the heart in heartland in this sitcom about a middle-class family living in the Midwest.
When and Where: Wednesday, Sept. 30 at 8:30 p.m. on ABC
Modern Family
What: Three wildly different families (spoiler alert: they're all related to each other) do their darnedest to cope with contemporary life. (Note: In our humble opinion, there is no TV justice if Modern Family doesn't turn into a big hit.)
When and Where: Wednesday, Sept. 23 at 9 p.m. on ABC
NCIS: Los Angeles
What: CBS sure loves franchise TV series. NCIS: Los Angeles, starring Chris O'Donnell and LL Cool J, is the first spinoff of NCIS, which itself was a spinoff of JAG.
When and Where: Tuesday, Sept. 22 at 9 p.m on CBS
Three Rivers, CBS
What: Alex O'Loughlin (Moonlight) and Katherine Moennig (The L Word) star in this sentimental organ-donation drama.
When and Where: Sunday, Oct. 4 at 9 p.m. on CBS
Trauma
What: Derek Luke (Antwone Fisher) and Cliff Curtis (Whale Rider) star this drama about San Francisco paramedics that features stuff blowing up good on a weekly basis.
When and Where: Monday, Sept. 28 at 9 p.m. on NBC
V, ABC
What: Elizabeth Mitchell stars (yay! and sniff) as a Homeland Security agent trying to stop alien reptiles and their human youth recruits—including her son—from taking over Earth in this remake of the 1980s sci-fi miniseries.
When and Where: Tuesday, Nov. 3 at 8 p.m. on ABC
The Vampire Diaries
What: Small-town life, homesick vamps and reincarnated hotties intersect in The Vampire Diaries, the latest entry in the TV vampire derby.
When and Where: Thursday, Sept. 10 at 8 p.m. (CW)
Get more photos of Vampire Diaries, Melrose Place and The Beautiful Life in our CW's Sexy New Shows gallery.