Glee
Could bisexual cheerleaders Santana Lopez (Naya Rivera) and Brittany S. Pierce (Heather Morris), aka "Brittana," be the hit musical drama's one true pairing?
90210
Jessica Lowndes and celeb scion Rumer Willis lock lips on the teen-show retread.
Desperate Housewives
Dana Delany told our Marc Malkin of her relationship with Julie Benz's Robin, "This is the first time on Wisteria Lane that you'll see two women doing more than just kissing."
Heroes
Madeline Zima's Gretchen put the moves on Hayden Panettiere's Claire, but the former cheerleader wasn't all that interested in a freshman fling.
Legend of the Seeker
This kiss between Triana (Charisma Carpenter) and Cara (Tabrett Bethell) was more about domination than romance, but it was still kind of sexy anyway, yes?
Gossip Girl
Does the liaison between Vanessa (Jessica Szohr) and Olivia (Hilary Duff) still count as situational lesbianism if Dan Humphrey (Penn Badgley) is in the middle? You tell us.
10 Things I Hate About You
Bianca (Meaghan Martin) and Dawn (Ally Maki) made out in front of a webcam as part of a moneymaking scheme.
Grey's Anatomy
When first we met her, Callie (Sara Ramirez) was straight, but after her breakup with George (T.R. Knight), the orthopedic surgeon found happiness with Arizona Robbins (Jessica Capshaw).
Bones
After ending her engagement with Hodgins (T.J. Thyne), Angela (Michaela Conlin) briefly hooked up with fellow artist Roxie Lyon (Nichole Hiltz).
The O.C.
Mischa Barton is no stranger to onscreen sapphic experimentation. Before Marissa Cooper hooked up with Olivia Wilde's Alex on The O.C., Mischa hooked up with Evan Rachel Wood's Jessie on Once and Again.
Buffy the Vampire Slayer
We'll put up Tara (Amber Benson) and Willow (Alyson Hannigan) as the best TV lesbians ever, but vote below to tell us what you think.
Want more? Click through our Gays on TV gallery!