10. Kristen Stewart
"Don't be an a--hole. That's my [relationship] advice. Don't be mean. Don't take s--t. Don't settle." (Glamour)
9. Justin Timberlake
"The only thing pot does for me is it gets me to stop thinking. Sometimes I have a brain that needs to be turned off. Some people are just better high." (Playboy magazine)
8. Brad Pitt
"You know, honey, it's not that bad."—Angelina Jolie quoting baby daddy's critique of her script for In the Land of Blood and Honey (Vanity Fair)
7. Ryan Gosling
"I'm not that good-looking. I think I'm a pretty weird-looking guy."—Humble (or delusional?) hottie after not being named People's Sexiest Man Alive (Chicago Sun-Times)
6. Ricky Gervais
"Two heterosexual actors pretending to be gay, so the complete opposite of some famous Scientologists."—Describing Jim Carrey and Ewan McGregor's roles in I Love You, Phillip Morris at the Golden Globes
5. Madonna
"I absolutely loathe hydrangeas. He obviously doesn't know that."—Withering rebuff of a fan's gift at Venice Film Fest
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4. Katy Perry & Salma Hayek (tie)
"Please, Jesus, give me some boobs!"—Hayek's girlhood prayers (The Graham Norton Show)
"I started praying for [my breasts] when I was, like, 11, and God answered that prayer above and beyond, by, like, 100 times, until I was like, 'Please, stop, God. I can't see my feet anymore. Please stop!'"—(Perry to Rolling Stone)
3. George Clooney
"I didn't live my life the right way for politics, you know. I f--ked too many chicks and did too many drugs, and that's the truth."—On running for office (Newsweek)
2. Christina Aguilera
"What so proudly we watched at the twilight's last reaming."—Flubbing national anthem before Super Bowl XLV
1. Charlie Sheen
"I am on a drug. It's called Charlie Sheen. It's not available. If you try it once you will die. Your face will melt off and your children will weep over your exploded body."—On Good Morning America, just one of the Warlock's winning contributions to the pop culture lexicon.