Blackie
Hugo helmer Martin Scorsese came to his animal actor's defense when the Doberman was snubbed by the first Golden Collar Awards for Best Dog in a Theatrical Film.
Roly & Ellie
The labradors who actually live at Highclere Castle, where Downton Abbey is filmed, were reportedly quite territorial around Roly, who plays Pharaoh on the show. Ellie was brought on to replace him, but star and dog-lover Hugh Bonneville figured the show's eagle-eyed fans would notice that Pharaoh was male and Ellie is female, so "the backstory is that Pharaoh passed away and we now have Isis," he tells the Daily Mail.
Uggie
Known for his roles in The Artist and Water for Elephants, the Jack Russell Terrier was adopted by animal trainer Omar Von Muller.
Cosmo
The rescued Jack Russell Terrier played Christopher Plummer's dog Arthur in Beginners. Costar Ewan McGregor became so smitten with the pup, that at the end of filming, he went out and adopted a little poodle mix named Sid. "I found my dog on the last day of the shoot," McGregor says. "He is gorgeous and my little Cosmo replacement."
Clark Griswold
The Dutch Shepherd mix star of the YouTube hit "Utimate Dog Tease" is another rescue pup and he was indeed named after the Vacation character.
Giggy
Lisa Vanderpump's not-quite-furry (hence the sweaters) Pomeranian is perhaps the biggest breakout star of Real Housewives of Beverly Hills.
Paddington
The golden retriever plays Duke in the current Bush's Baked Beans commercials. The original Duke was cast in ads back in 1994 because his ears instantly perked up every time Jay Bush said, "Roll that beautiful bean footage."
Marley
It took 18 different canine actors to play author Josh Grogan's mischievous real-life dog in the film adaptation of his best-seller Marley & Me.
Madison & Pono
Two pups played Vincent on Lost. Showrunners Damon Lindelof and Carlton Cuse noted that Vincent didn't have any daddy issues, which made him unique among the Lost characters.
Moonie
The Chihuahua cutie starred as Bruiser in both Legally Blonde films.
Happy
Another rescue pup, Happy played a character with the same name on 7th Heaven.
Gidget
The Chihuahua became a pop-culture fave in her series of ads for Taco Bell with the catchphrase "¡Yo quiero Taco Bell!"
Moose & Enzo
It was a father-son duo who stole the show as Eddie on Frasier. Enzo took over for dad around season nine when Moose retired from showbiz.
Maui
The collie mix, who portrayed Murray on Mad About You, is—you guessed it—also a rescued shelter dog.
Buddy
This golden retriever starred as both Comet on Full House and as Buddy in the Air Bud movies. Talk about working like a dog!
Honey Tree Evil Eye
Bud Light's frat-house party animal Spuds MacKenzie was actually played by a veddy proper female purebred Bull Terrier.
Bingo
In the original cartoon, Annie's pal Sandy was a mutt, but in the 1982 film, he was played by a purebred Otterhound.
Higgins & Benjean
A shelter dog and his son were just two of the pups who played Oprah's favorite onscreen pup, Benji, in a series of movies from 1974 to 2004.
Tiger
This rescue replaced the original Tiger on The Brady Bunch, who passed away in the middle of filming the "Katchoo" episode, and kept his character's name.
Pal, Lassie Junior, Spook, Baby, Mire & Hey He
Lassie was played by eight generations of lads. Male collies were preferred because of their thicker summer coat and their bigger size better accommodated growing children actors.
Terry
The female Cairn Terrier appeared in 15 movies throughout her life, most notably starring as The Wizard of Oz's Toto.
Skippy
The fox terrier starred as Asta in The Thin Man and as George in Bringing Up Baby.
Pal the Wonder Dog
The first of several dogs to play Pete in the Our Gang-The Little Rascals franchise, Pal had a natural ring around his eye. Later Peteys had the circle drawn on by Old Hollywood makeup master Max Factor.
Rin Tin Tin
The German Shepherd was adopted from a World War I battlefield and went on to star in 23 movies.