Inside Isabella Strahan's Inspiring Yearlong Cancer Battle

Among the gifts 20-year-old Isabella Strahan received this year: A healthy dose of perspective. Having successfully battled a fast-growing brain tumor, she said, "I feel like I've grown in many ways."

By Sarah Grossbart Dec 25, 2024 3:00 PM
| Updated Dec 27, 2024 3:28 PM
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Watch: Inside Isabella Strahan’s Inspiring Cancer Battle

No matter what Michael Strahan and his ex wife Jean Muggli may wrap up under the tree, safe to say their daughter Isabella Strahan has already received her greatest gift this year. 

Eight months after the 20-year-old University of Southern California student was diagnosed with medulloblastoma, a fast-growing malignant brain tumor, she endured her last chemotherapy treatment at Duke Children's Hospital & Health Center in North Carolina this past June and was declared officially cancer-free after a successful MRI a month later. 

“I feel like I’ve grown in many ways," Isabella told Town & Country this October, one year after a series of headaches, nausea and the inability to walk straight led her to the doctor for a thorough checkup that turned into a months-long battle for her life. "I’m super-­grateful for walking and talking again. You don’t think of the things you can do until you live without them."

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Michael Strahan's Family Tree

And these days she's making the most out of every last one of those freedoms, throwing herself completely into college life in Los Angeles

Whether it's decorating her new digs, covering herself in all things USC cardinal and gold or booking a limo to take her and twin sister Sophia Strahan to Disneyland to mark their 20th birthday in the Happiest Place on Earth, "Now I don’t say no to anything," the model told the outlet. "I don’t think, I’ll do it next week. You don’t know what next week will look like.”

Instagram/Isabella Strahan

Though her medical team has given her hope to be at least a little forward-thinking. 

While she still struggles with a bit of double vision and gaining back the weight she lost while undergoing three craniotomies and four rounds of chemo, “My doctors have told me they don’t think it will recur, which is very reassuring,” Isabella said of her cancer. “I’m happy to be here. I think this year has made me stronger. The people in your life are what makes it enjoyable."

And while she was tight with her Super Bowl-winning pop—also dad to daughter Tanita Strahan, 33, and Michael Strahan Jr., 30, with first wife Wanda Hutchins—before, he now makes it a point to huddle up with his squad whenever possible. 

“We’ve always been a close family, but this last year has given me some perspective," the Good Morning America cohost acknowledged to Town & Country. "At the end of the day the most important thing is your kids, your family, your mom, your father, your other loved ones—and just to hold them close to you, and your friends as well."

So while, no doubt, they'll have themselves a merry little Christmas, the former defensive end is eagerly rushing into life's more mundane moments as well.

“Now I wake up every day and enjoy that day," he told the mag, "more so than looking to next week, next month, or next year.”

And as the family readies themselves to turn the page on what was a very painful chapter, we're looking back on everything that led to their happily ever after. 

Brain Cancer Diagnosis

Isabella Strahan—the daughter of former couple Michael Strahan and Jean Muggli—said she "didn't notice anything was off" about her health until early October 2023, when she started experiencing headaches and nausea.

After throwing up blood one day, she got a full checkup and MRI scan at the urging of her dad. The results showed medulloblastoma, a malignant brain tumor found in children.

Later that month, she underwent brain surgery to remove the mass.

Family Support

Isabella went public with her diagnosis in a January 2024 interview with her dad and ABC News' Robin Roberts.

"I literally think that in a lot of ways, I'm the luckiest man in the world because I've got an amazing daughter," Michael noted at the time. "I know she's going through it, but I know that we're never given more than we can handle and that she is going to crush this."

Isabella's twin sister Sophia Strahan also offered her support. "I'm so lucky to have the most amazing sister and best friend in the world," she wrote on Instagram. "The last few months have been so much harder than we could have ever imagined, but it's made me realize just how strong you are"

Radiation Therapy

Following her interview, Isabella shared she had finished her round of radiation therapy.

"I'm very excited to finally be done," she said in a January 2024 YouTube video. "It's been a long six weeks and I'm very happy to finally heal my head after all of this because the side effects and everything get to you."

First Chemotherapy Round

Following radiation therapy, Isabella began undergoing chemotherapy to treat her cancer.

"My whole mouth feels like I got one giant root canal," she shared in a February 2024 vlog. "Every single tooth, just ripped out and not even surgically put back in. My jaw hurts, the bottom of my tongue hurts. It hurts when I gulp water." 

Still, the teen kept her spirits up, joking in a video posted a week later that her hair is "insufficient now."

"Besides being bald," she said, "it doesn't bring me pain mentally." 

Emergency Skull Surgery

Though Isabella was initially scheduled to undergo her second round of chemotherapy in early March 2024, she underwent emergency surgery on her skull—during which doctors drained out extra fluid from her head and replaced a bone they had originally cut out with a titanium plate—which pushed her chemo back by weeks.

"I'm in so much pain," she said in a vlog. "My face is extremely puffy, and this sucks. I was in so much pain earlier. I was, like, screaming."

Special Visit

Isabella's dad Michael arranged for her favorite singer Bryson Tiller to stop by their New York City home as a pick-me-up amid her treatments in March 2024.

"You haven't moved this much in months!" Michael joked to his daughter in her vlog of the visit. "You are fangirling right now."

 

Chemotherapy Round 2

Isabella shared in a March 2024 video that she had started her second round of chemotherapy, meaning there was "just four more" rounds to go.

New Side Effects

Amid her second chemotherapy round, Isabella said she began experiencing difficulties in walking.

"I literally can't walk without being lightheaded or out of breath," she shared in a March 2024 vlog, lamenting that there isn't an "anti-exhaustion medicine" she could take.

 

Good News

The YouTuber had a positive update after finishing her second round of chemotherapy, sharing that she would only have to undergo two more rounds of instead of the originally scheduled four.

"These are happy tears," she said in a video posted in April 2024. "It's not even considering crying when it's happy tears."

Roadblock in Her Journey

However, Isabella hit a bump in the road in her treatment plan when she had to undergo a third craniotomy. According to the teen, this procedure was unlike anything she had previously experienced.

"Not going to lie, I've been crying a lot," she detailed in an April 2024 vlog. "They sunk a needle in three spots and drained fluid, and I was completely awake for this. So, my first completely awake surgery."

Third Time's the Charm?

Not so much. Detailing the results of her third round of chemotheraphy, Isabella revealed her appetite was nonexistant. "Last week, it just dropped to zero," Isabella said in a May 2024 video. "So, it's annoying."

And though she was struggling with memory loss as well, she was able to dig into the bright side of the experience. "Tomorrow is really my last day of chemo," Isabella noted, "and then it's my last cycle, and then I'm done. It's insane."

A Crowning Achievement

Isabella picked up her crown to celebrate the end of her chemo treatments. "Just finished chemo," she wrote in a June 2024 TikTok video, which she captioned, "Did it."

The timing meant the University of Southern California student—who celebrated by ringing the bell after walking through a confetti parade—could have a bit of a summer break

"I'm so happy cause I thought I'd be done at the end of July," she explained. "I was supposed to do six rounds in total. And then I really would just have to go straight back to school. I'm so happy."

Sharing that she had her chemo port removed in a July 2024 YouTube vlog, she acknowledged the area was still a bit sore. However, she reasoned, "The recovery for this seems to be four weeks of not going in water and stuff like that, just kind of being careful, and scar care. So not too bad." 

Officially Cancer Free

Isabella was obviously relieved to have a "great, great scan" after finishing her chemotherapy, sharing in a video posted to her YouTube channel July 2024 that "everything was clear. Cancer-free. And everything is great."

Still, she acknowledged, "I miss my doctors already and everyone who's helped. Because they're all so nice. I feel like I'm just saddened today knowing that I wasn't gonna be going back for a while 'cause I love them so much."

Happiest Place on Earth

Now that she was officially cancer-free, what else could Isabella do except go to Disneyland? Her Super Bowl-winning dad joined her and twin sis Sophia to mark their joint 20th birthday a few days early in October 2024. 

The college student also celebrated another key milestone. 

“365 days since my life changed tremendously,” she captioned a shot of herself in a cap, gown, and mask, lying in a hospital bed on her Instagram Story. Adding another pic of all the balloons and flowers she received, she added, “Thankful for the progress I’ve made.”  

"The Life I Fought For"

In a September 2024 TikTok video, Isabella shared clips from throughout her cancer journey, including her lying in a hospital bed, relearning how to walk and the aftermath of her freshly shaved head. However, the second half of the video featured snippets of her smiling alongside her Kenneth Cole modeling campaign, enjoying an oceanside hike and going on a run, which she was unable to do while sick.

In addition to the clips, H.E.R.’s song “The Journey” played throughout the TikTok, which says, “Going through hell, but still, you're gonna make it through. It's the fire that they can't put out inside.”

In the caption of the post, Isabella triumphantly wrote, “Living the life I fought for.”