10. Hilary Duff vs. Faye Dunaway
When Dunaway was told that Duff will be part of the Bonnie and Clyde remake, she offered her input: "Couldn't they at least cast a real actress?" Yikes! Duff fired back with, "I might be mad if I looked like that now, too." Ouch! Sizzle! Burn!
9. Kid Rock vs. Steven Tyler
How's this for being honest? "I think it's the stupidest thing he's ever done in his life," is how Kid Rock described Tyler's move to take a seat judging on American Idol. And how did the Aerosmith rocker respond? "He's just jealous." Good point! Also, consider that he might be rubber and you may be glue...
8. Jennifer Aniston vs. Joan Collins
What's with older women putting down younger (and classier) ladies!? Collins decided to offer her insight on Aniston's looks, saying she's, "cute. But I wouldn't call her beautiful." Pft! And you wouldn't imagine what Aniston said back when she heard! She said: Nothing. Not that's classy.
7. Zack Galifianakis vs. Robert Downey Jr.
Costars don't have to get along. RDJ and Z.G. may have been together for Due Date, but when it came to Mel Gibson making a cameo in The Hangover 2, the duo divided. Downey believed in second chances (Mel game him one) and Galifianakis believed in not having crazy, racist men on set. For some reason, Zach's reasoning prevailed.
6. John Mayer vs. Jessica Simpson
Mayer went on and on in a Playboy interview about how amazing Jessica was in bed, comparing her to cocaine and calling her "sexual napalm." Jess may have been proud of her above-and-beyond performance, but she didn't want the whole world to know! But rather than lash out and make things worse, she simply told Oprah: "I'm a little bit angry."
5. Kathy Griffin vs. Bristol Palin
It seems like everyone's after the Palins! But Griffin really stirred things up with Bristol when she called her the "white Precious" during the VH1 Divas' Salute the Troops special. The DWTS runner up was ready to fire back, as usual, but didn't have to! The crowd booed Griffin's joke.
%20from%20Top%2010%20Feuds%20of%202010%20on%20E!%20Online)
4. Bill O' Reilly vs. Kim Kardashian (feat. Justin Bieber)
Bill has some opinions, sure, and they can get people upset. Like how he said that Muslims killed us on 9/11 and made the ladies from The View storm off stage. Or how he said being a single mom is "destructive to society" and got Jen Aniston to fire back.
But the Biebs, Bill? The angry old man went after J. and K. and their seductive-ish Elle photos, saying that, when he was 16, he'd rather play ball than hang out with hot starlets. His loss, right? Kim shot back.
3. Chelsea Handler vs. Angelina Jolie
It's rare when Chelsea verbally attacks someone (yeah, right), but she upped the ante during her comedy show in Newark when she called Ange the C-word! GASP! After all the reaction that followed, the E! host reminds us that this isn't something new.
2. Rick Sanchez vs. Jon Stewart
So, CNN anchor Sanchez went on the radio and whined about being the victim of some giant Jewish media conspiracy—and called Stewart a "bigot." That's just the sort of thing that'll get you fired, right? And sorry Rick, apologies won't get your job back. But you can spend your new free time listening to Stewart rip on you, and studying what not to say to keep next job.
1. Kanye West vs. George Bush
Kanye has a big mouth, shocker. Well, in 2005 his words got him some heat at the White House when he said Bush "doesn't care about black people" on live TV. This year, Bush made his book tour all about Kanye and his presidential "disgust" with the rapper's words. The two went at it again, and then made up—kinds. Oh, but now the rapper has a beef with Today's Matt Lauer. Oh boy...
Next gallery: Top 10 Craziest Housewives of 2010